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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Anthocyanins
drug:
Leptin
Research Papers that Mention the Interaction
“ Anthocyanin treatment failed to reverse the effects of the high fat diet on body weight and glucose tolerance, but significantly reduced the leptin and IL-6 levels.”
Effect of Anthocyanin-Rich Tart Cherry Extract on Inflammatory Mediators and Adipokines Involved in Type 2 Diabetes in a High Fat Diet Induced Obesity Mouse Model“In rodent studies and in … adipocytes, it was observed that anthocyanins regulated the carbohydrate metabolism in the body due to the upregulation of GLUT4 (insulinregulated glucose transporter) translocation, increased activation … proliferator-activated receptor-γ) in adipose tissue and skeletal muscles as well as increased secretion of adiponectin and leptin.”
“Treated adipocytes with anthocyanins enhanced adipocytokine (adiponectin and leptin ) secretion and up-regulated the adipocyte specific gene expression without activation of PPARgamma in isolated rat adipocytes.”
Anthocyanin enhances adipocytokine secretion and adipocyte-specific gene expression in isolated rat adipocytes.“In addition, anthocyanins were found to potently inhibit the expression of adipocyte-specific genes, including adipocyte fatty acid-binding protein, leptin , and fatty acid synthase.”
Inhibition of Adipocyte Differentiation by Anthocyanins Isolated from the Fruit of Vitis coignetiae Pulliat is Associated with the Activation of AMPK Signaling Pathway
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