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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Anthocyanins
drug:
Hydrogen Peroxide
Research Papers that Mention the Interaction
“Further, the anthocyanins and C3G have been shown to prevent neuro-toxicities induced by different toxic factors, such as lipopolysaccharide, hydrogen peroxide , ethanol, kainic acid, acrolein, glutamate, and scopolamine.”
Neuroprotective effects of anthocyanins and its major component cyanidin-3-O-glucoside (C3G) in the central nervous system: An outlined review.“ H2O2 increased the expression of BAX, BAD, p53 and caspase-3 in a time-dependent manner, those of which anthocyanin significantly decreased.”
“In vitro incubation with anthocyanins or hydroxycinnamic acids (HCA) (0.5 and 0.05 mg/ml) was found to enhance significantly RBC resistance to H2O2 (100 microM) induced ROS production.”
“… ANT … H2O2 led to the activation of signaling pathways, including the extracellular signal-regulated protein kinases 1 and 2 (ERK1/2) and Akt, whereas it significantly (… and suppressed the activation of the nuclear factor-kappa B (NF-κB) subunits, p50 and p65, which are transcription factors responsible for inflammation.”
“ AC could reverse the decrease of cell viability induced by H2O2 and efficiently suppressed cellular ROS production and cell apoptosis.”
Protective Effects of Anthocyanins from Coreopsis tinctoria against Oxidative Stress Induced by Hydrogen Peroxide in MIN6 Cells“In the pot experiment (40-day-old …), treatment with 7.5 g L−1 anthocyanin resulted in … of ·O2−, H2O2 , and malondialdehyde contents in rice leaves, while the activities of superoxide dismutase, peroxidase, catalase, and … peroxidase were increased by 59.10, 23.81, 41.75, and 9.39%, respectively.”
Surface spraying of anthocyanin through antioxidant defense and subcellular sequestration to decrease Cd accumulation in rice (Oryza sativa L.) grains in a lead–zinc mine area“Additionally, moderate oxidative stress from H2O2 exposure induced the synthesis of polyphenolic antioxidants including flavonol and anthocyanin.”
“In this study, we found that the concentrations of anthocyanin and flavonoids were significantly induced by H2O2 treatment.”
“The enzymatic degradation of anthocyanin was eventually enhanced coupled with the oxidative activities of peroxidase (POD) and H2O2.”
“Moreover, abiotic stresses all enhanced the production of H2O2 and exogenous H2O2 addition significantly increased the anthocyanin concentration and UVR8 transcription, while these increases were severely inhibited by addition of dimethylthiourea (DMTU, a chemical trap for H2O2).”
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