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“ Local anesthetics have also been reported to have an inhibitory effect on other ion channel-coupled receptors, including 5-HT3, GABA, glycine, and nicotinic ACh receptors.”
Masui. The Japanese journal of anesthesiology • 2013 | View Paper
“The local anesthetic lidocaine (0.3 mM) also noncompetitively inhibited nicotinic agonist-induced secretion without inhibiting elevated K+-induced secretion.”