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Last Updated: 4 months ago

Possible Interaction: Anesthetics, Local and Epinephrine

Research Papers that Mention the Interaction

The addition of either epinephrine or sodium bicarbonate to the local anaesthetic enhances the efficacy of epidural block.
British journal of anaesthesia  •  2003  |  View Paper
The inclusion of epinephrine in the local anesthetic resulted in a persistence of these changes.
Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics  •  2001  |  View Paper
The addition of epinephrine reduced systemic absorption of LA.
British journal of anaesthesia  •  2017  |  View Paper
Adverse reactions are frequent, but most of them are attributed to vasovagal reflexes or hemodynamic changes after the injection of LAs with epinephrine.
The journal of allergy and clinical immunology. In practice  •  2016  |  View Paper
Epinephrine has been shown to prolong sensory nerve blockade and delay systemic uptake of local anesthetics , thus reducing the risk of anesthetic toxicity.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists  •  2014  |  View Paper
CONCLUSIONS If optimal visualization is desired, the ideal time for the surgeon to begin the incision should be 25 minutes after injection of local anesthetic with epinephrine.
Plastic and reconstructive surgery  •  2013  |  View Paper
Most dermatologists refrain from use of epinephrine with local anesthetics for digital blocks.
Journal francais d'ophtalmologie  •  2012  |  View Paper
injection of a local anaesthetic test dose were significantly influenced by epinephrine.
British journal of anaesthesia  •  2012  |  View Paper
Our case report suggests that the impaired clearance mechanisms in postmastectomy skin with an underlying implant can lead to ischemia when using local anesthetic with epinephrine.
Aesthetic Plastic Surgery  •  2010  |  View Paper
Maintaining blood flow to a partially demyelinated nerve may eliminate one etiology involved in the "double-crush phenomenon") Remote from these vascular properties, epinephrine may also enhance local anesthetic induced nerve toxicity.
Canadian journal of anaesthesia = Journal canadien d'anesthesie  •  2008  |  View Paper
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