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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Anesthetics, Local
supplement:
Choline
Research Papers that Mention the Interaction
“Utilizing platelets whose … have found that local anesthetics , chlorpromazine and propranolol block: (a) formation of 14C-thromboxane B2, 14C-prostaglandins and 14C-hydroxyacids (12-L-hydroxy-5,8,…) from endogenous (phospholipid) 14C-archidonate; and (b) block the fall in the 14C-arachidonate content of platelet phospholipids, especially phosphatidyl choline.”
Local anesthetics, chlorpromazine and propranolol inhibit stimulus-activation of phospholipase A2 in human platelets.
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