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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Anesthetics, General
supplement:
Glycine
Research Papers that Mention the Interaction
“Background: GLIC , a pentameric ligand-gated ion channel (pLGIC), is inhibited by general anesthetics , but in anesthetic-bound crystal structures the channel appears open.”
“ GLIC , a prokaryotic pLGIC homologue, is inhibited by general anesthetics , suggesting anesthetics stabilize a closed channel state, but in anesthetic-bound GLIC crystal structures the channel appears open.”
Propofol Binding to the Resting State of the Gloeobacter violaceus Ligand-gated Ion Channel (GLIC) Induces Structural Changes in the Inter- and Intrasubunit Transmembrane Domain (TMD) Cavities*“ GLIC is a prokaryotic cation pLGIC and can be inhibited by clinical concentrations of general anaesthetics.”
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