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Discover Supplement-Drug Interactions

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Last Updated: 4 months ago

Possible Interaction: Anesthetics, General and Glycine

Research Papers that Mention the Interaction

Background: GLIC , a pentameric ligand-gated ion channel (pLGIC), is inhibited by general anesthetics , but in anesthetic-bound crystal structures the channel appears open.
GLIC , a prokaryotic pLGIC homologue, is inhibited by general anesthetics , suggesting anesthetics stabilize a closed channel state, but in anesthetic-bound GLIC crystal structures the channel appears open.
The Journal of Biological Chemistry  •  2013  |  View Paper
GLIC is a prokaryotic cation pLGIC and can be inhibited by clinical concentrations of general anaesthetics.
The Biochemical journal  •  2013  |  View Paper