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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Androstenedione
drug:
Triiodothyronine
Research Papers that Mention the Interaction
“Addition of androstenedione (500 ng/mL) to the culture medium enhanced 25 ng T3 induced testosterone and oestradiol secretions.”
“While androstenedione potentiated the stimulatory effect of T3 (25 ng) on LH (25 ng) induced testosterone and oestradiol secretions, it reversed the inhibitory effect of 50 ng T3 on LH mediated testosterone secretion which was accompanied by a decrease in oestradiol secretion.”
T3 directly stimulates basal and modulates LH induced testosterone and oestradiol production by rat Leydig cells in vitro.“ T3 significantly increased (P < 0.01) both delta5-DHEA to delta4-androstenedione and delta5-pregnenolone to delta4-P4 conversion in Leydig cells indicating stimulation of 3beta-HSD activity.”
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