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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Androstenedione and Phenobarbital

Research Papers that Mention the Interaction

Treatment of the animals with repeated doses of phenobarbitalin vivo caused an enhanced rate of formation of 5α-androstane-3,17-dione and of polar metabolites from this steroid.
Naunyn-Schmiedebergs Archiv für Pharmakologie  •  2005  |  View Paper
Phenobarbital administration to rabbits resulted in 49-fold and 23-fold increases in the transformation of androst-4-ene-3,17-dione and dehydroepiandrosterone, respectively, into estriol by lymphocytes.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme  •  1982  |  View Paper
For instance, the administration of phenobarbital or chlorcyclizine to rats increases several fold the ability of liver microsomes to hydroxylate testosterone and Δ4-androstene-3,17-dione.
Advances in enzyme regulation  •  1963  |  View Paper