Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 5 years ago

Possible Interaction: Androstenedione and Melatonin

supplement:

Androstenedione

supplement:

Melatonin

Research Papers that Mention the Interaction

“ Melatonin caused a dose-dependent inhibition (P<0.05) of LH+insulin-like growth factor 1 (IGF1)-induced androstenedione and progesterone production.”
Reproduction, fertility, and development  •  2018  |  View Paper
“In the presence of 100 microM melatonin, androstenedione and progesterone were increased whereas estradiol was not influenced.”
Toxicology  •  2006  |  View Paper
“In vitro, FGA blocked aromatization ability, and melatonin inhibited both androstenedione and estradiol production, but a further treatment with eCG partly restores the steroid secretion.”
Domestic animal endocrinology  •  1999  |  View Paper
“The addition of melatonin to incubations inhibited androgen formation from pregnenolone and, at the higher level of concentration, favoured androstenedione at the expense of testosterone.”
Steroids  •  1971  |  View Paper