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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Androstenedione
Research Papers that Mention the Interaction
“Furthermore, the levels of pregnenolone, androstenedione , testosterone and dihydrotestosterone were significantly diminished in all samples collected after the administration of DMPA.”
Studies on ovarian and adrenal steroids at different phases of the menstrual cycle. III. Steroid and lutropin levels before and after the administration of a single contraceptive dose of depot-medroxyprogesterone acetate (DMPA).“ MPA , when used in a mixture with testosterone and/or 4-androstenedione in vitro, acted as a competitive inhibitor of the reduction of these substrates.”
“Rat oral mucosa microsomal delta4-3-ketosteroid-5alpha-A-ring reductase enzyme system, reducing testosterone and 4-androstenedione , was found to be inducible by systemic administration of medroxyprogesterone acetate (MPA).”
Effect of progestins on androgen delta4-3-ketosteroid-5alpha-A-ring reductase system in rat oral mucosa.“ MPA also significantly increased the rate of reduction of Δ4-androstenedione , cortisol, progesterone and MPA itself (all Δ4-3-ketosteroids) when used as substrates in vitro.”
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