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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Androstenedione and Epinephrine

supplement:

Androstenedione

supplement:

Epinephrine

Research Papers that Mention the Interaction

Splanchnic nerve activation as well as perfusion with EPI provoked a significant release of cortisol, aldosterone and androstenedione.
Endocrine research  •  1995  |  View Paper
Perfusion of the isolated adrenals with epinephrine (10(-7) to 10(-5) M) stimulated androstenedione release in a dose-dependent manner.
…,epinephrine … androstenedione in a dose-dependent manner with an ED50 of 0.75 x 10(-6) M. The maximal effect was reached at 10(-5) M … h. The epinephrine-stimulated androstenedione release was abolished by the beta-adrenergic antagonist propranolol while the alpha-adrenergic antagonist phentolamine had no effect.
Neuroendocrinology  •  1994  |  View Paper
hCG stimulation of the patient’s adrenal cell cultures significantly increased cyclic adenosine monophosphate, corticosterone, 11-deoxycortisol, cortisol, and androstenedione production.
Journal of the Endocrine Society  •  2017  |  View Paper