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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Androstenedione
drug:
Danazol
Research Papers that Mention the Interaction
“When administered to adult human males in doses of 200 or 600 mg daily, Danazol produced decreases in plasma levels of testosterone (T) and androstenedione (A) which were dose related.”
Pituitary and testicular function studies. I. Experience with a new gonadal inhibitor, 17-alpha-pregn-4-en-20-yno-(2,3-d)isoxazol-17-ol (Danazol).“ Danazol has been reported to act as an interference in the immunoassay measurement of various androgens (including androstenedione ), resulting in falsely elevated values for these hormones (5).”
“Concentrations of danazol as low as 1 micrometer suppressed LH-stimulated testosterone and androstenedione production in cultured Leydig cells.”
Danazol inhibits steroidogenesis in the rat testis in vitro.
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