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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Androstenedione
drug:
Cyproterone
Research Papers that Mention the Interaction
“The plasma levels of SBP-unbound testosterone and of delta 4-androstenedione were significantly suppressed by CPA , while DHEAS was not significantly reduced.”
[Combination of cyproterone acetate and natural estrogens in the treatment of hirsutism].“Levels of plasma testosterone, sex hormone binding globulin, free testosterone (derived) and androstenedione fell significantly on high dose CA and this reduction was maintained during low dose therapy.(ABSTRACT TRUNCATED AT 250 WORDS)”
“Biologically, testosterone and delta-4 androstenedione levels were significantly decreased with cyproterone acetate and spironolactone compared to no treatment.”
“ Androstenedione did not increase after ACTH stimulation (21.5 and 32.1 nmol/L, respectively) and did not decrease after dexamethasone inhibition (21 and 29 nmol/L, respectively), but only decreased after cyproterone acetate treatment (8 and 10.8 nmol/L, respectively).”
“The addition of cyproterone to the incubation medium inhibited the biosynthesis of androstenedione , whereas 17 alpha-hydroxypregnenolone and dehydroepiandrosterone increased.”
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