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Last Updated: 2 years ago

Possible Interaction: Androstenedione and Adrenocorticotropic Hormone

Research Papers that Mention the Interaction

Plasma androstenedione levels were also increased by ACTH injection, but DHT treatment seemed to little affect.
The Journal of veterinary medical science  •  2009  |  View Paper
ACTH treatment caused a significant increase in plasma levels of cortisol, progesterone, androstenedione and testosterone in all mares (P<0.05).
Animal reproduction science  •  2007  |  View Paper
Androstenedione levels were lower (P<0.001) and increased less after ACTH treatment in ovariectomized mares, as compared to when intact (P<0.05).
Animal reproduction science  •  2007  |  View Paper
In humans and cynomolgus monkeys the administration of ACTH and/or glucocorticoids does not increase peripheral aromatization, but results in a slight decrease in the aromatization of androstenedione.
Steroids  •  1987  |  View Paper
Interestingly, the production of two androgens, androstenedione and 11β-hydroxyandrostenedione (11OHA), that were also produced in large amounts under basal conditions significantly increased after ACTH incubation.
The Journal of endocrinology  •  2011  |  View Paper
Trophoblast cell cultures treated with increasing amounts of corticotrophin releasing hormone and urocortin 1 showed increased secretion of E2 in the presence of androstenedione.
Reproductive Sciences  •  2009  |  View Paper
ACTH also stimulated the adrenal gland to secrete androstenedione and testosterone.
The Journal of clinical investigation  •  2006  |  View Paper
Controls carrying Arg148 alleles had lower 11-deoxycortisol and 17-hydroxyprogesterone concentrations, a lower response of androstenedione to 1-24 adrenocorticotropin , and an almost significant decrease in free testosterone levels, suggesting that Arg148 alleles in the gp130 gene have a protective effect against androgen excess and adrenal hyperactivity.
Obesity research  •  2003  |  View Paper
In response to adrenocorticotropin hormone , plasma levels of 17-OHP, androstenedione and androstenedione/cortisol were significantly higher in patients than in controls.
The Journal of Steroid Biochemistry and Molecular Biology  •  2001  |  View Paper
Moreover, in patients with adenomas, cortisol, 17-OH progesterone, and androstenedione responses to corticotropin were significantly increased (P < 0.001, all), whereas dehydroepiandrosterone sulfate levels were significantly lower at baseline, with blunted response to corticotropin (P < 0.001, both).
The Journal of clinical endocrinology and metabolism  •  2000  |  View Paper
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