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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Andrographolide and Carboplatin

Research Papers that Mention the Interaction

At the sublethal concentration, andrographolide increased carboplatin sensitivity of Hep-2 cells by increasing carboplatin-induced apoptosis and inhibiting cell viability.
Taken together, … indicate that andrographolide, … carboplatin , synergistically inhibited cell proliferation and induced mitochondrial apoptosis of Hep-2 cells by increasing the intracellular ROS, regulating the mitogen-activated protein … phosphatidylinositol 3-kinase (PI3K/AKT) pathways, altering the BCL2/BAX ratio, and ultimately activating the cleavage of Caspase-3 and PARP.
Anti-cancer drugs  •  2019  |  View Paper