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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Ampicillin
supplement:
Quinine
Research Papers that Mention the Interaction
“Conclusions Quinine therefore, reduced the bioavailability and the antimicrobial activity of ampicillin –cloxacillin upon co-administration, which may have therapeutic implications.”
Significant Pharmacokinetic Interactions Between Quinine and Ampicillin–Cloxacillin Combination“Chloroquine and quinine increased ampicillin activity, with increasing concentrations extending the antibacterial’s inhibition zones by 2.7-4.4 mm and from 1.1 to over 60 mm, respectively.”
“ Quinine and, to a lesser extent, chloroquine increase the activity of ampicillin and potentially other β-lactams, which has implications for combined clinical use.”
Quinoline Antimalarials Increase the Antibacterial Activity of Ampicillin
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