supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
drug:
Ampicillin
supplement:
Glucose
Research Papers that Mention the Interaction
“MIC(90) against ampicillin was 32-fold higher in glucose added urine than MIC(90) in broth.”
The influence of glucose added urine on the in vitro antimicrobial activity of various antibiotics.“ Ampicillin was, however, found to be unstable in dextrose 5%, and it would be preferable for it not to be added to dextrose infusions.”
“These studies demonstrate that diuresis resulting from administration of dextrose in water plus ampicillin starting 4 or 21 days after intravenous injection of enterococci reduces renal titers more than ampicillin or diuresis alone.”
Influence of water diuresis on antimicrobial treatment of enterococcal pyelonephritis.“The addition of glucose to the culture medium was shown to simultaneously increase the level of LPE and minimum inhibitory concentration (MIC) for ampicillin of Y. pseudotuberculosis cells 6- and 2-fold, respectively.”
Relationship between Adaptive Changing of Lysophosphatidylethanolamine Content in the Bacterial Envelope and Ampicillin Sensitivity of Yersinia pseudotuberculosis“ Glucose caused catabolite repression of cell luminescence up to the late stationary phase, and ampicillin enhanced this effect.”
“In single-drug admixtures, aztreonam loss under both storage conditions was less than 10% but ampicillin loss was more than 10% in 0.9% sodium chloride injection and more than 50% in 5% dextrose injection.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback