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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
drug:
Amphotericin B
supplement:
Mechlorethamine
Research Papers that Mention the Interaction
“Abstract In HT29 human colon carcinoma cells, amphotericin B at doses above 120μg/ml increased nitrogen mustard uptake, and this was due to an increase in the apparent V max without a change in the apparent K m .”
“Longer incubations (24 to 48 hr) of ascites fluid human ovarian carcinoma cells or SKMES-1 human epidermoid carcinoma cells with amphotericin B 4μg/ml enhanced the uptake of nitrogen mustard to a greater degree than that observed when cells were incubated for only 30 min.”
“Therefore, amphotericin B can enhance nitrogen mustard by human tumor cell lines and by fresh human tumor cells.”
Amphotericin B (Fungizone R) enhancement of nitrogen mustard uptake by human tumor cells.
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