“ ISO at non‐antifungal concentration interacts synergistically with amphotericin B (AMB) and fluconazole (FLC), but the combination with flucytosine (5‐FC) showed no interaction.”
“In conclusion, AMB and FLC enhanced the antifungal potency of ISO through oxidative stress when used in synergy.”
“In contrast, ISO with AMB synergistically stimulated membrane permeabilization compared to ISO/FLC.”