Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
“The clearance (CL) of AmB in dextrose (0.039 ± 0.016 liter · h−1 · kg−1) was significantly lower (P < 0.005) than the CL of AmB in lipid emulsion (0.062 ± 0.024 liter · h−1 · kg−1).”
“The steady-state volume of distribution for AmB in dextrose (0.83 ± 0.33 liter · kg−1) was also significantly lower (P < 0.005) than that for AmB in lipid emulsion (1.47 ± 0.77 liter · kg−1).”
Antimicrobial Agents and Chemotherapy • 1999 | View Paper
“The effect of glucose on intracellular ionized magnesium was blocked by amphotericin B and the EC(50) of the effect of glucose on intracellular ionized magnesium was about 5 mmol/l of glucose.”
“Ultrafiltration due to the osmotic gradient induced by the dextrose content of the dialysis solution increased significantly to 0.31 mL/kg/min with amphotericin B , compared with control values of 0.18 mL/kg/min.”
American journal of kidney diseases : the official journal of the National Kidney Foundation • 1984 | View Paper
“Addition of amphotericin B after exposure to cholera toxin or to the hypertonic solutions resulted in a further significant reduction of absorption of glucose and ethylene glycols (p less than 0.05).”
“In the colon the administration of amphotericin B after the exposure to cholera toxin resulted in enhanced absorption of glucose (p less than 0.05) in spite of continuing fluid secretion.”
The Journal of laboratory and clinical medicine • 1983 | View Paper
“With exponential phase cells, in the presence of AmB , the consumption of glucose and the production of ethanol, trehalose, and glycerol continuously decreased with time, and after 25 min, the metabolism was blocked.”
Canadian journal of microbiology • 1996 | View Paper
“ Amphotericin B was shown to have the following effects on metabolism in intact yeasts: inhibition of endogenous O 2 uptake; inhibition of oxidation of glucose and acetate; possible alteration of cell permeability; inhibition of glycolysis.”