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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Amphotericin B
supplement:
Fat Emulsion
Research Papers that Mention the Interaction
“Even if we do not know how the constituents of a fat emulsion affect the solubility of amphotericin B , the fact that we observed a yellow precipitate indicates that the mixture is not stable.”
“We have observed that a yellow precipitate starts to form wtihin 2 hours after preparing a mixture of 45 mg of amphotericin B and 500 mL of fat emulsion.”
Antiarrhythmic Drug Plasma Concentrations in Ambulatory Patients“The pharmacokinetic of AmB was significantly modified and renal toxicity and infusion-related side effects were reduced when the drug was prepared in fat emulsion.”
Comparison of conventional and lipid emulsion formulations of amphotericin B: Pharmacokinetics and toxicokinetics in dogs.“Even if we do not know how the constituents of a fat emulsion affect the solubility of amphotericin B , the fact that we observed a yellow precipitate indicates that the mixture is not stable.”
“We have observed that a yellow precipitate starts to form wtihin 2 hours after preparing a mixture of 45 mg of amphotericin B and 500 mL of fat emulsion.”
Amphotericin B is Incompatible with Lipid Emulsions
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