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Last Updated: 4 years ago

Possible Interaction: Amphetamine and Yohimbine

supplement:

Amphetamine

supplement:

Yohimbine

Research Papers that Mention the Interaction

The stimulant amphetamine also reduced submissive behavior while yohimbine (also a stimulant), and the antianxiety agent diazepam had no such effect.
Pharmacology Biochemistry and Behavior  •  2005  |  View Paper
The interaction between yohimbine and amphetamine is unlikely to be due to noradrenergic mechanisms but could conceivably involve serotonergic or dopaminergic mechanisms.
There was a mutual potentiation between the toxicities of yohimbine and amphetamine.
Psychopharmacology  •  2004  |  View Paper
The adrenergic blocking agents yohimbine and dibenamine, though ineffective on their own, antagonized the action of amphetamine and tyramine.
Psychopharmacologia  •  2004  |  View Paper
The effects of both modafinil and amphetamine were enhanced by a pretreatment with yohimbine (1 mg/kg, i.p.),
Brain Research  •  1992  |  View Paper
Likewise, yohimbine prevented the potentiation of the morphine Straub tail reaction by amphetamine , being about 1 170 as active as naltrexone.
Life sciences  •  1982  |  View Paper
The hypotensive action of amphetamine was blocked by piperoxan or yohimbine (α‐adrenoceptor blocking agents) and by haloperidol which is known to block central adrenoceptors.
The Journal of pharmacy and pharmacology  •  1972  |  View Paper