Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Amphetamine and Valproic Acid

supplement:

Amphetamine

Research Papers that Mention the Interaction

Furthermore, co-administration of BA or VPA with amphetamine produced additive effects on histone H4 acetylation as well as CREB phosphorylation in the striatum.
Neuroscience  •  2008  |  View Paper
Li reversed AMPH changes in NT-3 in the reversal model, and VPT prevented AMPH changes in NT-3 in the prevention model.
Journal of psychiatric research  •  2008  |  View Paper
In amphetamine-pretreated animals, valproate administration reversed citrate synthase activity inhibition induced by amphetamine.
Progress in Neuro-Psychopharmacology and Biological Psychiatry  •  2007  |  View Paper
We found that repeated administration of VPA or BA for 6 days inhibited the expression of sensitized response following amphetamine challenge.
Behavioural Brain Research  •  2007  |  View Paper
However, the co-administration of lithium or valproate with amphetamine increased lipid peroxidation, depending on the brain region and treatment regimen.
Journal of psychiatry & neuroscience : JPN  •  2006  |  View Paper
In this study, we tested the hypotheses that lithium and valproate would reverse and prevent the behavioral and biochemical effects of amphetamine , using a rat model of mania.
Behavioural pharmacology  •  2006  |  View Paper
Although the association of VPA plus amphetamine alters some proteins involved in the JNK pathway in the hippocampus, these alterations were very random and seemed that were not related to the d-AMPH-induced manic-like behavior.
Heliyon  •  2019  |  View Paper