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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Amphetamine and Taurine





Research Papers that Mention the Interaction

At the highest dose, amphetamine increased extracellular glutamate by 445% of baseline as well as extracellular concentrations of taurine , and reduced extracellular concentrations of glutamine.
Neurochemical Research  •  2004  |  View Paper
The administration of d‐amphetamine (5.0 mg/kg × 4 ip) caused gradual fivefold increases in the extracellular glutamate and taurine levels and moderate increases in the extracellular aspartate level.
We conclude that a massive increase in extracellular taurine reflects hyperactivation of glutamatergic neurotransmission elicited by acute toxic dose of d‐amphetamine.
Annals of the New York Academy of Sciences  •  2002  |  View Paper
Amphetamine also produced an enhancement on GABA and taurine levels, although these increases did not follow a dose-related curve.
Brain Research Bulletin  •  1993  |  View Paper
Increased locomotor and behavioral activities following a high dose of amphetamine elevated taurine concentrations significantly in the substantia nigra and locus ceruleus.
Journal of neurochemistry  •  1986  |  View Paper