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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Amphetamine
drug:
Tamoxifen
Research Papers that Mention the Interaction
“As the symptoms of amphetamine treatment in rodents are believed to mimic the symptoms of a manic episode, many of the preclinical studies for this indication have demonstrated that tamoxifen inhibits amphetamine action.”
Tamoxifen and amphetamine abuse: Are there therapeutic possibilities?“In rats, tamoxifen , the only PKC inhibitor that crosses the blood-brain barrier, decreased the risk-taking behavior and hyperactivity induced by amphetamines [1].”
Protein kinase C inhibition: a target for treatment of mania.
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