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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Amphetamine and Substance P



Research Papers that Mention the Interaction

The rotational responses to both dynorphin A and substance P were potentiated by injection of amphetamine 1 h later, suggesting that both peptides act via nigro-striatal dopamine neurons.
Experimental Brain Research  •  2004  |  View Paper
significantly attenuated amphetamine (1.25 and 2.5 mg/kg, i.p.)-stimulated striatal preprodynorphin and, to a lesser degree, substance P messenger RNA expression.
Neuroscience  •  1996  |  View Paper
As measured by quantitative in situ hybridization, acute amphetamine induced an increase in substance P , preproenkephalin A and dynorphin messenger RNA levels (+23 +/- 0.05%, +45 +/- 0.07% and +24 +/- 0.05%, respectively).
Chronic amphetamine treatment enhanced only substance P and dynorphin messenger RNA levels (+23 +/- 0.04% and +42 +/- 0.04%, respectively).
Neuroscience  •  1995  |  View Paper