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Last Updated: 3 years ago

Possible Interaction: Amphetamine and Streptozocin

supplement:

Amphetamine

Research Papers that Mention the Interaction

Gamma-hydroxybutyrate and amphetamine were less potent after streptozotocin while the potency of raclopride, quinpirole, ketamine, haloperidol and cocaine was not significantly changed by streptozotocin.
While markedly affecting locomotion, body weight and blood glucose, streptozotocin only modestly affected sensitivity to the behavioral effects of amphetamine and other drugs; these results fail to confirm previous reports of decreased behavioral actions of stimulants in diabetic rats.
European journal of pharmacology  •  2008  |  View Paper
In the second study, streptozotocin only decreased amphetamine self-administration thereby supporting the view that streptozotocin does not simply decrease the potency of amphetamine.
Streptozotocin significantly decreased the number of amphetamine infusions without changing the number of cocaine infusions or food pellets received.
Neuroendocrinology  •  2003  |  View Paper
Rats made diabetic with streptozotocin showed decreased stereotyped behaviors following administration of amphetamine or apomorphine.
Behavioral neuroscience  •  1985  |  View Paper