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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Amphetamine
drug:
Saccharin
Research Papers that Mention the Interaction
“We report … that amphetamine (1.0 mg/kg) may acquire discriminative control over the preference of … for a distinctive flavour when its administration precedes access to a saccharin solution (0.15% w/v), versus the occasions when the injection … saline precedes no toxicosis after access to the same flavour.”
Discriminative stimulus properties of amphetamine in a conditioned taste aversion paradigm“Conditioned taste aversions induced by pairing the consumption of saccharin with an amphetamine injection are attenuated in rats with depletion of central catecholamines caused by intraventricular administration of 6-hydroxydopamine (6-OHDA).”
“After amphetamine injections were terminated, subsequent saccharin vs. water preference testing showed that the amphetamine injections given after but not the injections given before resulted in a long-term aversion to the saccharin solution.”
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