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Last Updated: 2 months ago

Possible Interaction: Amphetamine and Raclopride



Research Papers that Mention the Interaction

Amphetamine (1 mg/kg) increased and raclopride (0.3 mg/kg) decreased performance by 63 and 28 %, respectively, with a 20-min injection-test interval.
Psychopharmacology  •  2015  |  View Paper
ResultsSCH 23390, SCH 39166, haloperidol, and raclopride dose-dependently inhibited vocalizations under AMPH and suppressed the proportion of trill calls.
Psychopharmacology  •  2012  |  View Paper
In the first set of experiments, all types of AIMs (axial, limb, orolingual and locomotor) were markedly reduced when amphetamine was co-administered with either the D(2) dopamine receptor antagonist raclopride or the D(1) receptor antagonist SCH23390.
Neurobiology of Disease  •  2009  |  View Paper
Even though the group given SCH23390 or raclopride alone showed profound disruption on DRL behavior by flattening the IRT curve, the co-administration of amphetamine with SCH23390 or raclopride reversed the aforementioned amphetamine-induced behavioral deficiency on DRL task.
The Chinese journal of physiology  •  2007  |  View Paper
The administration of amphetamine (1 mg/kg) induced a clear CPP that was completely blocked by the DA antagonists flupentixol (0.25 mg/kg) or raclopride (0.125 mg/kg).
Behavioral neuroscience  •  2004  |  View Paper
A reduction of 20-30% in raclopride binding was observed 30 min after amphetamine injection (4 mg/kg i.p.).
Synapse  •  2004  |  View Paper
ResultsAdministration of raclopride or clozapine reversed either an amphetamine or a ketamine-induced PPI deficit, as had the novel mood stabilizer lamotrigine in previous studies.
Psychopharmacology  •  2003  |  View Paper
Amphetamine elicits DA release, provoking a rapid increase in synaptic DA and leading to a reduction in raclopride binding, which outlasts the temporary increase in extracellular DA concentrations by several hours.
Biological Psychiatry  •  2003  |  View Paper
In contrast, the D2 receptor-selective antagonist raclopride induced RGS2 mRNA when administered alone and greatly enhanced stimulation by amphetamine.
Journal of neurochemistry  •  1999  |  View Paper
Conversely, the effects of cocaine and amphetamine on PVT Fos expression were blocked by pretreatment with the dopamine D2/3 antagonist raclopride.
The Journal of Neuroscience  •  1998  |  View Paper
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