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Possible Interaction: Amphetamine and Pimozide

supplement:

Amphetamine

Research Papers that Mention the Interaction

Pimozide and lithium alter behavior and the behavioral effects of amphetamine , but neurotransmitters other than NE may be involved.
Psychiatry Research  •  1979  |  View Paper
The latter action of amphetamine was blocked by pimozide.
Polish journal of pharmacology and pharmacy  •  1983  |  View Paper
Like other neuroleptics, pimozide antagonises many of the actions of amphetamine and apomorphine, such as stereotyped behaviour and emesis, but it is not so effective as haloperidol or chlorpromazine in protecting animals against lethal doses of noradrenaline.
Single oral doses of pimozide , 5 to 20mg, reduced the subjective euphoric response to subsequent intravenous injections of amphetamine in abusers of the drug.
Drugs  •  1976  |  View Paper
The antistereotypic abilities of haloperidol, fluphenazine and pimozide were most marked against amphetamine , but this was not a consistent observation for thioridazine, clozapine and sulpiride.
Psychopharmacologia  •  1975  |  View Paper
Single doses of clozapine, risperidone, and pimozide all markedly decreased calling under saline and AMPH.
Psychopharmacology  •  2012  |  View Paper
The effects of pimozide, clonidine and amphetamine were approximately additive amphetamine cancelled the effects of pimozide and clonidine, while clonidine augmented the effect of pimozide).
Pharmacology Biochemistry and Behavior  •  1987  |  View Paper
The inhibition by amphetamine of the release of [3H]ACh elicited by electrical stimulation at 1 Hz involves dopamine receptors and can be fully antagonized by clozapine, haloperidol, chlorpromazine, or pimozide.
Journal of neurochemistry  •  1985  |  View Paper
Such activity seemed related to a catecholaminergic substrate since the increase of responding induced by amphetamine was blocked by pimozide , d,l-propranolol and prazosin.
Psychopharmacology  •  1983  |  View Paper
Pimozide and moperone although antagonizing the behavioral changes of amphetamine , maintained its antiulcer activity.
Pharmacology  •  1977  |  View Paper
When amphetamine treatment was suspended in Phase IV, pimozide accelerated the extinction, especially in those groups that had previously received the 1.0 mg/kg dose of amphetamine.
Psychopharmacology  •  1977  |  View Paper
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