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Last Updated: 3 years ago

Possible Interaction: Amphetamine and Phenoxybenzamine

Research Papers that Mention the Interaction

alpha-Adrenoceptor blocking agents: phenoxybenzamine , phentolamine and aceperone, potentiated and prolonged amphetamine and apomorphine stereotypy in the rat, but inhibited the amphetamine hypermotility.
Polish journal of pharmacology and pharmacy  •  1977  |  View Paper
Phenoxybenzamine (4 mg/kg) constricted primarily the pupil of the innervated iris and completely antagonized the effects of the catecholamines on the irides and amphetamine on the nictitating membranes, but only partially antagonized amphetamine-induced mydriasis.
Psychopharmacology  •  2004  |  View Paper
Phenoxybenzamine (5 mg/kg) reduces the inhibitory action of amphetamine on the bradykinin-induced activity in the ventrolateral columns.
Farmakologiia i toksikologiia  •  1982  |  View Paper
Haloperidol (2.0 mg/kg), propranolol (10 mg/kg) and phenoxybenzamine (30 mg/kg) were tested for ability to antagonize the lethal effects of amphetamine and its derivatives.
Research communications in chemical pathology and pharmacology  •  1978  |  View Paper
5 d‐Propranolol, chlorpromazine and phenoxybenzamine antagonized the glycogenolytic effect of amphetamine only when administered in sedative doses.
British journal of pharmacology  •  1971  |  View Paper
Chlorpromazine and phenoxybenzamine partially antagonized the sharp rise in temperature following the administration of amphetamine , and also significantly reduced mortality.
British journal of pharmacology and chemotherapy  •  1962  |  View Paper
The analeptic effect of amphetamine was significantly inhibited by phenoxybenzamine (1.0 to 2.0 mg/kg), chlorpromazine (1.0 to 2.0 mg/kg), and Dibenamine (10 to 20 mg/kg).
The Journal of pharmacology and experimental therapeutics  •  1961  |  View Paper