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Last Updated: 3 years ago

Possible Interaction: Amphetamine and Pargyline



Research Papers that Mention the Interaction

When combining amphetamine and pargyline treatment, H2O2 production was accelerated in the initial phase but dropped to control levels at 30 min.
International journal of sports medicine  •  2004  |  View Paper
The reuptake inhibitors, nomifensine, dichlofensine and amphetamine , in the presence of pargyline , a monoamine oxidase inhibitor, stimulated both basal and K(+)-evoked release of DA from the SME and PP under static incubation conditions.
Brain Research  •  1991  |  View Paper
Bound spin labeled amphetamine was also displaceable by pargyline.
Pargyline was found to inhibit binding of spin labeled amphetamine by cytosolic monoamine oxidase.
The acetylenic monoamine oxidase inhibitors, pargyline and clorgyline, have been used to modulate the binding of spin labeled amphetamine.
Biochimica et biophysica acta  •  1983  |  View Paper
4 The administration of amphetamine 4 h after pargyline resulted in a decrease in brain glycogen similar to that seen after amphetamine alone.
British journal of pharmacology  •  1979  |  View Paper
Pargyline was less effective in potentiating the stimulant actions of amphetamine , and had no significant effect on the disappearance of amphetamine from the brain.
European journal of pharmacology  •  1971  |  View Paper
Nialamide, pargyline and tranylcypromine, three monoamine oxidase inhibiting drugs, and the microsomal enzyme inhibitor SKF 525‐A significantly decreased the amount of amphetamine removed from the portal circulation of the isolated perfused liver of the cat.
The Journal of pharmacy and pharmacology  •  1970  |  View Paper
The degree of potentiation of amphetamine toxicity by monoamine oxidase inhibitors varied from one to another, the range being from pargyline , which increased the toxicity of amphetamine about 3-fold, to mebanazine which increased it about 100-fold.
European journal of pharmacology  •  1969  |  View Paper
Injection of amphetamine (2 mg), but not Cholecystokinin octapeptide, in rats pretreated with pargyline increased the concentration of 3‐methoxytyramine in the dorsal striatum and this effect was blocked by pretreatment with α‐methyl‐ρ‐tyrosine.
Journal of neuroendocrinology  •  1992  |  View Paper