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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Amphetamine
drug:
Nitroarginine
Research Papers that Mention the Interaction
“Systemic injection of the … (NO) synthase inhibitor NG-nitro-L-arginine (LNO) prevents the … of amphetamine ( Amph ) on prepulse inhibition (PPI), a sensorimotor gating model in which the amplitude of the acoustic startle … (ASR) to a startling sound (pulse) is reduced when preceded immediately by a weaker stimulus (prepulse).”
Nitric oxide modulates dopaminergic regulation of prepulse inhibition in the basolateral amygdala“SKF38393 had no significant effect on PPI whether … preceded by l-NOARG.ConclusionsOur findings show that l-NOARG interacted … Amph , an indirect DA agonist, but not with the direct DA agonists on PPI, suggesting that … is involved on the dopaminergic modulation of sensorimotor gating, probably by a presynaptic mechanism.”
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