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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Amphetamine and Morphine



Research Papers that Mention the Interaction

Morphine increased the Pentobarbital-Chlorpromazine-Alcohol Group, Amphetamine , the Lysergic Acid Diethylamide and the Morphine-Benzedrine Group scores and decreased Benzedrine Group scores on the Addiction Research Center Inventory.
The Journal of pharmacology and experimental therapeutics  •  1994  |  View Paper
An antagonism between morphine and amphetamine is demonstrated but the anti-amphetamine effect of morphine is different from that of the neuroleptic drugs.
Psychopharmacologia  •  2004  |  View Paper
In male rats morphine dependence also increases amphetamine-stimulated locomotor activity (open-field), increases amphetamine brain levels, and decreases in vitro metabolism of aniline.
Psychopharmacology  •  2004  |  View Paper
Amphetamine (2 mg/kg) treatment potentiated morphine withdrawal aggression.
Psychopharmacologia  •  2004  |  View Paper
This paper discusses evidence that the analgesic effects of morphine and amphetamine in the formalin test are synergistic, and depend on dopaminergic neurotransmission involving the dopamine cells of the ventral tegmental area.
Neuroscience & Biobehavioral Reviews  •  1989  |  View Paper
Morphine antagonized rotation by either apomorphine or amphetamine in both syndromes.
Brain Research  •  1983  |  View Paper
Amphetamine insignificantly diminished the development of tolerance to cataleptogenic effects of morphine in rats but markedly inhibited the development of tolerance to morphine-induced hyperactivity in mice.
Polish journal of pharmacology and pharmacy  •  1983  |  View Paper
Antinociceptive action of morphine and codeine was antagonized by apomorphine and amphetamine.
Polish journal of pharmacology and pharmacy  •  1981  |  View Paper
In the morphine‐dependent animal the circling rate to amphetamine given 4 days after morphine was first implanted was depressed but after withdrawal with naloxone a day later the rate increased, returning to normal after 21 days.
The Journal of pharmacy and pharmacology  •  1978  |  View Paper
Morphine , codeine and fentanyl slightly inhibited apomorphine stereotypy, and evidently antagonized stereotypy produced by amphetamine.
Polish journal of pharmacology and pharmacy  •  1977  |  View Paper
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