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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
supplement:
Amphetamine
drug:
Morphine
Research Papers that Mention the Interaction
“ Morphine increased the Pentobarbital-Chlorpromazine-Alcohol Group, Amphetamine , the Lysergic Acid Diethylamide and the Morphine-Benzedrine Group scores and decreased Benzedrine Group scores on the Addiction Research Center Inventory.”
A dose-response analysis of the subjective, psychomotor and physiological effects of intravenous morphine in healthy volunteers.“An antagonism between morphine and amphetamine is demonstrated but the anti-amphetamine effect of morphine is different from that of the neuroleptic drugs.”
“In male rats morphine dependence also increases amphetamine-stimulated locomotor activity (open-field), increases amphetamine brain levels, and decreases in vitro metabolism of aniline.”
“ Amphetamine (2 mg/kg) treatment potentiated morphine withdrawal aggression.”
“This paper discusses evidence that the analgesic effects of morphine and amphetamine in the formalin test are synergistic, and depend on dopaminergic neurotransmission involving the dopamine cells of the ventral tegmental area.”
“ Morphine antagonized rotation by either apomorphine or amphetamine in both syndromes.”
“ Amphetamine insignificantly diminished the development of tolerance to cataleptogenic effects of morphine in rats but markedly inhibited the development of tolerance to morphine-induced hyperactivity in mice.”
“Antinociceptive action of morphine and codeine was antagonized by apomorphine and amphetamine.”
“In the morphine‐dependent animal the circling rate to amphetamine given 4 days after morphine was first implanted was depressed but after withdrawal with naloxone a day later the rate increased, returning to normal after 21 days.”
“ Morphine , codeine and fentanyl slightly inhibited apomorphine stereotypy, and evidently antagonized stereotypy produced by amphetamine.”
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