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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Amphetamine
drug:
Modafinil
Research Papers that Mention the Interaction
“Three double-blind placebo-controlled trials using modafinil , bupropion and naltrexone have shown positive results in reducing amphetamine or methamphetamine use.”
Pharmacological approaches to methamphetamine dependence: a focused review.“ MD pretreatment improved oxidative status of VTA and striatum after AMPH exposure.”
“Pretreatment with a lower modafinil dose (32 mg/kg) augmented the discriminative stimulus properties of cocaine (1.6 mg/kg dose group) and amphetamine.”
Modafinil evokes striatal [(3)H]dopamine release and alters the subjective properties of stimulants.“an inhibitor of catecholamine synthesis, almost completely prevented the effects of amphetamine (0.25 and 1 mg/kg), but only slightly reduced the duration of the waking effect of modafinil (2.5 and 5 mg/kg).”
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