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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Amphetamine
drug:
Metoclopramide
Research Papers that Mention the Interaction
“In contrast, metoclopramide dose-dependently decreased amphetamine-induced stereotypy, locomotion, rearing, and sniffing up, and concurrently antagonized the suppression of lying down produced by amphetamine.”
Opposite effects of sulpiride and metoclopramide on amphetamine-induced stereotypy.“Haloperidol, metoclopramide and to a lesser extent, SCH-23393 together with peripheral amphetamine injections produced a locomotor bias that resulted in ipsilateral turning.”
Locomotor bias produced by intra-accumbens injection of dopamine agonists and antagonists“The ability of the dopamine D1 antagonist, SCH ….0 mg/kg) or the D2 antagonist, metoclopramide (1.0, 10.0, 20.0 mg/… with either the nonselective dopamine agonist, amphetamine (2.0 mg/kg), the D1 agonist, SKF 38393 (10.…, quinpirole (1.0 mg/kg), was evaluated in rats.”
“Conversely, unilateral intrafrontocortical microinjections of the antagonist, metoclopramide (25 and 100 micrograms in 1.0 microliter) resulted in ipsiversive circling in amphetamine (1.5 mg/kg, i.p.)”
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