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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Amphetamine
drug:
Methamphetamine
Research Papers that Mention the Interaction
“However, the behavioral and neurophysiological correlates of methamphetamine and amphetamine administration are unique from one another, thereby suggesting these two compounds impact dopaminergic neurotransmission differentially.”
“Oxidative stress has been demonstrated to occur in response to high doses of substituted amphetamines such as methamphetamine ( METH ) and 3,4-methlyene-dioxymethamphetamine (MDMA).”
“Based on the analytical data obtained from 563 MAMP users, the cut-off value was found to be 0.97 ng/mg for the simultaneous detection of MAMP and amphetamine (AMP) ≥0.004 ng/mg (LOD).”
“The estimated percentage of the population that consumed cocaine in a community is similar to the conventionally estimated consumption of cocaine; however, the combined estimated population that consumed amphetamine and methamphetamine based on sewage epidemiology was ~2 to 4 fold higher than the conventional estimates.”
“In the two cases of methamphetamine bodypacking, the relevant serum concentrations of methamphetamine and amphetamine , which could be measured up to 9 days after ingestion, indicated a decrease of the methamphetamine/amphetamine ratios in an exponential manner.”
“Here we tested whether a ‘blunted’ response to amphetamine in methamphetamine ( MA ) users extends to D3-rich brain areas.”
“Relative to healthy controls, MA users had greater decreases in [11C]-(+)-PHNO binding (increased dopamine release) after amphetamine in D3-rich substantia nigra (36 vs 20%, p=0.03) and globus pallidus (30 vs 17%, p=0.06), which correlated with self-reported ‘drug wanting’.”
Heightened Dopaminergic Response to Amphetamine at the D3 Dopamine Receptor in Methamphetamine Users“However, many policy and prevention efforts surrounding amphetamine use disproportionately target methamphetamine users and women.”
“Absolute infant doses for methylamphetamine plus amphetamine (as methylamphetamine equivalents) were 17.5 microg kg(-1) day(-1) and 44.7 microg kg(-1) day(-1), respectively, for cases 1 and 2.”
“It appears likely that methamphetamine diffusion in Europe is impeded by a strong market for other stimulant drugs [cocaine, amphetamine and methylenedioxymethamphetamine (MDMA)].”
“ Amphetamine levels were found to vary widely in both populations, at all levels of methamphetamine.”
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