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“Coadministration of mecamylamine during pretreatment with nicotine, amphetamine , or cocaine prevented the development of this long-term hyperreactivity of nucleus accumbens dopamine neurons.”
“ Mecamylamine and pempidine (both 2 mg/kg intraperitoneally) slightly but significantly depressed the intensity of circling behaviour induced by amphetamine , but failed to modify the induced by apomorphine.”