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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Amphetamine
drug:
Lobeline
Research Papers that Mention the Interaction
“ Lobeline wag found to be more effective than a placebo, especially when combined with 8 milligrams of amphetamine.”
“Numerous studies have shown that lobeline inhibits both the neurochemical and behavioral effects of amphetamine in rodents, and behavioral studies demonstrate that lobeline has potential as a pharmacotherapy for psychostimulant abuse.”
“Objective: In preclinical studies, lobeline inhibited hyperactivity induced by nicotine and amphetamine , and improved performance and learning in studies utilizing radial-arm maze and spatial-discrimination water maze.”
“Based on its neurochemical mechanism, the ability of lobeline to functionally antagonize the neurochemical and behavioral effects of the psychostimulants amphetamine and methamphetamine was examined.”
A novel mechanism of action and potential use for lobeline as a treatment for psychostimulant abuse.“ Lobeline diminishes the behavioral and neurochemical effects of nicotine and amphetamines , and is considered a potential pharmacotherapy for drug abuse and addiction.”
Lobeline, a potential pharmacotherapy for drug addiction, binds to mu opioid receptors and diminishes the effects of opioid receptor agonists.
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