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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Amphetamine
drug:
Hexamethonium
Research Papers that Mention the Interaction
“Higher doses of hexamethonium decreased the sniffing response induced by amphetamine and the response induced by combination of amphetamine and nicotine.”
Effect of nicotine on sniffing induced by dopaminergic receptor stimulation“ Hexamethonium and methylatropine, also ineffective by themselves, potentiated the effect of amphetamine but not that of tyramine.”
“The results suggest that amphetamine and tyramine enhance pseudoconditioning through activation of a peripheral adrenergic mechanism and that amphetamine , in addition, triggers an opposing cholinergic mechanism, also peripheral, from which it can be released by the anticholinergic agents hexamethonium and methylatropine.”
Possible peripheral adrenergic and cholinergic mechanisms in pseudoconditioning
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