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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Amphetamine and Hexamethonium



Research Papers that Mention the Interaction

Higher doses of hexamethonium decreased the sniffing response induced by amphetamine and the response induced by combination of amphetamine and nicotine.
European Neuropsychopharmacology  •  2000  |  View Paper
Hexamethonium and methylatropine, also ineffective by themselves, potentiated the effect of amphetamine but not that of tyramine.
The results suggest that amphetamine and tyramine enhance pseudoconditioning through activation of a peripheral adrenergic mechanism and that amphetamine , in addition, triggers an opposing cholinergic mechanism, also peripheral, from which it can be released by the anticholinergic agents hexamethonium and methylatropine.
Psychopharmacologia  •  2004  |  View Paper