supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 4 years ago
supplement:
Amphetamine
drug:
Enzastaurin
Research Papers that Mention the Interaction
“Rats pretreated with enzastaurin 18 h, but not 3, prior to a self-administration session showed a decrease in the number of responses for AMPH , shifted the ascending limb of the amphetamine dose effect curve, and produced no change in responses for sucrose.”
The protein kinase Cβ-selective inhibitor, enzastaurin, attenuates amphetamine-stimulated locomotor activity and self-administration behaviors in rats“Pretreatment with 30 pmol enzastaurin or 6 mg/kg 6c decreased the number of AMPH infusions earned and breakpoints without altering sucrose-maintained behaviors.”
PKC inhibition decreases amphetamine-maintained responding under a progressive-ratio schedule of reinforcement.
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback