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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Amphetamine
Research Papers that Mention the Interaction
“Abstract After an injection of amphetamine (4 mg/kg) and l -dihydroxyphenylalanine (400 mg/kg) a high rate of upward jumping was observed in the treated mice when placed individually in glass jars.”
Effect of neuroleptic drugs on mouse jumping induced by l-DOPA in amphetamine treated mice“Dopamine synthesis in the ventral striatum, measured as L-dihydroxyphenylalanine formation after blockade of dihydroxyphenylalanine decarboxylase , was found to be reduced by approximately 60% after 2 weeks of amphetamine treatment and in animals withdrawn for 1 day or 7 days.”
Reduction of dopamine release and synthesis by repeated amphetamine treatment: role in behavioral sensitization.“We recently reported (Lal, Colpaert & Laduron, 1975) that a combination of amphetamine and L-3- 4-dihydroxyphenylalanine (L-dopa) reliably elicits mouse-jumping.”
“ Amphetamine and L‐dopa had a biphasic effect the initial fall being followed by a rise.”
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