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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Amphetamine
drug:
Cysteamine
Research Papers that Mention the Interaction
“While equimolar doses of methyl atropine failed to completely reproduce the effects of atropine … in an avoidance task, Carlton was apparently puzzled by the finding that MeA , like atropine, augmented … effects of amphetamine and that it produced an atropine-like slowing … the EEG" (Carlton and Didamo 1961, p 586).”
Central versus peripheral effects of muscarinic antagonists: the limitations of quaternary ammonium derivatives“ Cysteamine in doses ranging from 50-300 mg/kg reversed decreases in PPI induced by systemic injections of amphetamine (2 mg/kg).”
Cysteamine Blocks Amphetamine-Induced Deficits in Sensorimotor Gating“In addition, intra-accumbens infusions of cysteamine produced a slight reduction in the locomotor response induced by amphetamine.”
“Direct injections of cysteamine into the nucleus accumbens also decreased the locomotor response to amphetamine , and produced a local reduction in somatostatin levels in the accumbens.”
“ Systemic cysteamine also decreased the motor stimulant effects of amphetamine , without influencing the rewarding properties as determined by the conditioned place preference procedure.”
“ Systemic cysteamine injection mitigated the apomorphine-induced stereotypy as well as decreasing motor stimulant effects of amphetamine , which favor cysteamine over animal models of schizophrenia relative to hyperactivity of dopaminergic pathway.”
Therapeutic possibilities of cysteamine in the treatment of schizophrenia.
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