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Last Updated: 2 years ago

Possible Interaction: Amphetamine and Cocaine





Research Papers that Mention the Interaction

Here, we review presynaptic dopamine terminal alterations observed following self-administration of cocaine and amphetamine , as well as possible mechanisms by which these alterations occur and their impact on the progression of addiction.
ACS chemical neuroscience  •  2015  |  View Paper
This review describes commonly used methodologies to measure dopamine and baseline parameters of presynaptic dopamine regulation, including exocytotic release and reuptake through the dopamine …, as well as dramatic adaptations in dopamine neurotransmission and drug sensitivity that occur with acute non-contingent and chronic, contingent self-administration of cocaine … amphetamine.
Frontiers in bioscience  •  2013  |  View Paper
Both cocaine and amphetamines produce differential lasting behavioral alterations, that is, locomotor sensitization, depending on the time of the day they are administered.
International review of neurobiology  •  2009  |  View Paper
Amphetamine also led to an increase in intracellular Ca(2+) that was blocked by prior treatment with 5 microM thapsigargin or 10 microM cocaine.
Molecular pharmacology  •  2004  |  View Paper
Previous microscopic studies have shown that the length of dendrites and density of dendritic spines increased in the nucleus accumbens and frontal cortex after repeated exposure to amphetamine and cocaine , but the molecular mechanisms responsible are not well understood.
Annals of the New York Academy of Sciences  •  2002  |  View Paper
A relative catecholamine deficiency occurs following prolonged abuse of cocaine and amphetamine due to transporter upregulation and receptor downregulation.
Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology  •  1999  |  View Paper
It is likely that cocaine acted by inhibiting NE re-uptake, iproniazid by blocking MAO, and amphetamine by a combination of both these mechanisms.
Neuropharmacology  •  1970  |  View Paper
However, amphetamine lacks the ion channel-blocking properties of cocaine.
Cardiology in the Young  •  2017  |  View Paper
Correlations were detected between cocaine and amphetamine consumption (r2=0.98), and between heroin and cannabinoids (r2>0.82).
Environmental pollution  •  2011  |  View Paper
such complications are also known to be associated with abuse of cocaine , which is often spiked with amphetamines [2–4].
Clinical Neuroradiology  •  2011  |  View Paper
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