supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
supplement:
Amphetamine
drug:
Chlorpromazine
Research Papers that Mention the Interaction
“The results presented here show that chronic pretreatment of guinea pigs with chlorpromazine produces a persistent reduction in the amounts of amphetamine or apomorphine needed to induce stereotyped behavior.”
“ Chlorpromazine (0.25–1.0 mg/kg), haloperidol (0.25, 0.5 mg/kg), and physostigmine (0.04, 0.08 mg/kg), administered before the third amphetamine or cocaine injection, blocked the motor stereotypies and hyperactivity.”
“ Chlorpromazine , 2 mg/kg, potentiated the hypermotility caused by amphetamine as measured in jiggle cages.”
“In rats which were trained to eat during a 5-h period, all doses of chlorpromazine potentiated amphetamine anorexia.”
The effect of some CNS depressants on the hypermotility and anorexia induced by amphetamine in rats.“In chimpanzees, rocking movements can be increased by administration of amphetamine and reduced with chlorpromatine or barbiturates (2 , 3 ) .”
“It was found that the increase in CoBF induced by amphetamine is blocked by atropine or chlorpromazine.”
On the mechanism of the amphetamine induced vasodilatation at the rat's cerebral cortex“Antagonism between the effects of amphetamine and chlorpromazine on both response rate and accuracy measures of performance was found.”
“The effects of amphetamine and chlorpromazine on the rate of adjunctive behaviors may not be predictable from control rates.”
“ Chlorpromazine or cyproheptadine antagonized the “ amphetamine-state”.”
“Although amphetamine and ACTH produced no consistent effects, chlorpromazine caused a marked decrease in threshold.”
“Neuroleptic drugs chlorpromazine , haloperidol, tardan and clozapine), anxiolytic drugs (diazepam and meprobamate) and reserpine suppressed the rage reaction induced by APT in mice.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback