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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
supplement:
Amphetamine
drug:
Aripiprazole
Research Papers that Mention the Interaction
“We present 2 cases of presumed false-positive UDSs for amphetamines after ingestion of aripiprazole.”
Case Reports of Aripiprazole Causing False-Positive Urine Amphetamine Drug Screens in Children“Upon secondary analysis, … change in motor speed as assessed by the BACS (….05) for those receiving aripiprazole was greater than that for the placebo group, whereas deterioration in verbal fluency (p < 0.01) … function (p < 0.01) in those receiving aripiprazole was significantly greater than in the placebo group.”
“In Experiment 1, aripiprazole (20 mg) attenuated the discriminative stimulus and many of the subject-rated effects of amphetamine.”
“ Aripiprazole pre‐treatment resulted in bidirectional effects on amphetamine self‐administration.”
“Together, these results indicate that under conditions of dopaminergic stimulation, aripiprazole attenuates the reinforcing and psychomotor stimulant effects of d‐amphetamine , but the dose range for this effect is rather limited.”
Attenuation of reinforcing and psychomotor stimulant effects of amphetamine by aripiprazole“ Aripiprazole and amphetamine reduced both punished and unpunished responding.”
“All doses of aripiprazole were effective in preventing the motor stimulant effects of amphetamine and cocaine.”
“However, aripiprazole reversed prepulse inhibition deficits induced by amphetamine , but not by any of the other agents tested.”
“ResultsWithdrawal from repeated amphetamine injection reduced the breakpoint while low doses of aripiprazole (0.25 and 0.75 mg/kg) prevented this effect.”
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