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Possible Interaction: Amphetamine and Apomorphine



Research Papers that Mention the Interaction

CONCLUSION Long term use of amphetamine and apomorphine produces adaptive changes in 5-HT-1A receptor mediated functions, which are prevented by the co-use of 5-HT-1A agonists.
Progress in Neuro-Psychopharmacology and Biological Psychiatry  •  2013  |  View Paper
Administration of apomorphine (0.5 mg/kg) and amphetamine (2.5 mg/kg) after chronic low dose apomorphine treatment revealed an enhancement of their effects - stereotypy and aggressiveness was observed.
Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova  •  1982  |  View Paper
Apomorphine and amphetamine caused turning behaviour in the lesiond animals which was ipsiversive after DR lesions but contraversive after MR damage.
European journal of pharmacology  •  1979  |  View Paper
Rotation was not necessarily in the same direction with high and low doses of amphetamine, or amphetamine and apomorphine administered a week apart from each other.
Psychopharmacology  •  1976  |  View Paper
Prolonged pretreatment with suprathreshold doses of amphetamine decreased the threshold dosage of both amphetamine and apomorphine necessary to elicit stereotyped behavior.
Advances in neurology  •  1975  |  View Paper
The altered effects of apomorphine and amphetamine could indicate differential changes in dopamine receptor signalling leading to functional desensitisation, or altered modulation of sensory gating in the nucleus accumbens by limbic structures such as the hippocampus.
European Neuropsychopharmacology  •  2008  |  View Paper
Twenty-one days post unilateral stereotaxic injection of Tinuvin 123, systemic injection of both apomorphine and amphetamine caused rotations toward the side of the lesion in these rats.
Brain Research  •  2000  |  View Paper
In a second series of experiments, we sought to determine whether priming with these … selective dopamine receptor agonists, as well as the mixed D1/D2 agonist, apomorphine , would result in an enhanced stereotypy response to … subsequent administration of non-stereotypy producing doses of amphetamine (0.5-1.… mg/kg).
Brain research  •  1999  |  View Paper
Other doses of amphetamine (0.…-1.0 mg/kg) or apomorphine (0.1-1.0 mg/kg) produced a …-dependent generalization to the stimulus cue of amphetamine (1.0 mg/kg), and haloperidol (0.01-0.1 mg/kg) was able to prevent the stimulus control exerted by amphetamine.
Behavioural pharmacology  •  1997  |  View Paper
While no changes occurred when apomorphine was administered before amphetamine , the fencamfamine group showed intermediate alterations (nonsignificant changes in sniffing but a significant increase in rearing behavior).
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas  •  1995  |  View Paper
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