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“Since both tricyclic drugs inhibit the aromatic hydroxylation of amphetamine , these studies do not support the hypothesis that hydroxylated metabolites of amphetamine, p‐hydroxyamphetamine and p‐hydroxynorephedrine are essential for the peripheral sympathomimetic effects of amphetamine.”
The Journal of pharmacy and pharmacology • 1975 | View Paper
“Differences certainly occur (Table 3), withrates varying from zero to 20 per thousand patients per month, but they do not compensate, as the two heavy users of anti-depressants are also among the four heaviest users of amphetamines.”