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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Amphetamine and Anticonvulsants

Research Papers that Mention the Interaction

Two dopaminergic agonists, amphetamine (4 mg/kg) and apomorphine (16 mg/kg) enhanced rotation at anticonvulsant doses while the dopaminergic antagonist haloperidol reduced rotational behavior at a dose (1 mg/kg) which exacerbate seizure severity.
Pharmacology Biochemistry and Behavior  •  1981  |  View Paper
The two nonsedative anticonvulsants , diphenylhydantoin and phenacemide, markedly reduced amphetamine toxicity in aggregated mice, which suggests that these two anticonvulsant drugs may have mild tranquilizing properties.
Journal of pharmaceutical sciences  •  1962  |  View Paper
The anti-seizure property of the extract was potentiated by amphetamine.
African health sciences  •  2008  |  View Paper
In the electroshock test–taking hind‐limb tonic extension as the end point–apomorphine (10 mg/kg) exerted no effect on the anticonvulsant … diphenylhydantoin (DPH; 8 mg/kg); amantadine (25 and 100 mg/kg) decreased that of DPH, while L‐DOPA (500 mg/kg) and d lamphetamine (10 … anticonvulsants.
Epilepsia  •  1980  |  View Paper