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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Amphetamine
drug:
Anticonvulsants
Research Papers that Mention the Interaction
“Two dopaminergic agonists, amphetamine (4 mg/kg) and apomorphine (16 mg/kg) enhanced rotation at anticonvulsant doses while the dopaminergic antagonist haloperidol reduced rotational behavior at a dose (1 mg/kg) which exacerbate seizure severity.”
Handling-induced seizures and rotational behavior in the Mongolian gerbil“The two nonsedative anticonvulsants , diphenylhydantoin and phenacemide, markedly reduced amphetamine toxicity in aggregated mice, which suggests that these two anticonvulsant drugs may have mild tranquilizing properties.”
“The anti-seizure property of the extract was potentiated by amphetamine.”
Anti-seizure activity of the aqueous leaf extract of Solanum nigrum linn (solanaceae) in experimental animals.“In the electroshock test–taking hind‐limb tonic extension as the end point–apomorphine (10 mg/kg) exerted no effect on the anticonvulsant … diphenylhydantoin (DPH; 8 mg/kg); amantadine (25 and 100 mg/kg) decreased that of DPH, while L‐DOPA (500 mg/kg) and d lamphetamine (10 … anticonvulsants.”
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