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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Amphetamine
Research Papers that Mention the Interaction
“It should again be stressed that patients taking adrenergic neurone blockers (for example, guanethidine or bethanidine) must not be given (or themselves take) sympathomimetic drugs (such as ephedrine, phenylephrine, phenylpropanolamine and amphetamine ), as these can all acutely aggravate their hypertension.”
SOME OF THE CLINICALLY MORE IMPORTANT SIDE EFFECTS OF DRUG THEREPY. PART 1“Pretreatment with the α1-adrenergic-receptor antagonist Prazosin or lesion of the serotonergic system significantly reduced the locomotor hyperactivity and striatal Fos expression induced by Amphetamine.”
Interaction between the noradrenergic and serotonergic systems in locomotor hyperactivity and striatal expression of Fos induced by amphetamine in rats“P]These results support the hypothesis that amphetamine increases ACh output through the release of catecholamines from adrenergic nerve endings; these in turn stimulate a cholinergic pathway which ascends to the cerebral cortex, and either originates from or passes through the septum.”
“The antagonism of these two effects of amphetamine was studied by pretreatment with several neuroleptic, adrenolytic and cholinergic drugs.”
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